Betahistine Impurity 4 HCl CAS 88796-99-0 (free base)
| CAS No. | 88796-99-0 (free base) |
| Molecular Formula | C8H12N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Betahistine Impurity 4 HCl (CAS 88796-99-0 (free base), C8H12N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Betahistine Impurity 4 HCl (C8H12N2OHCl) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 188.66 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Betahistine Impurity 4 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O HCl |
| Molecular Weight | 188.66 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Betahistine Standards
- Betahistine EP Impurity A (CAS 100-69-6)
- Betahistine Impurity 01 DiHCl (CAS 101252-40-8)
- Betahistine EP Impurity B (CAS 103-74-2)
- Betahistine Impurity 12 (CAS 109-06-8)
- Betahistine impurity 41 (CAS 113985-59-4)
- Betahistine Impurity 45 (CAS 128225-22-9)
- Betahistine impurity 33 (CAS 13585-92-7)
- Betahistine Impurity 13 HCl (CAS 13585-92-7（free base）)
Recommended Standards
- Fluconazole EP Impurity I Bromide (CAS 150168-54-0)
- Nimodipine impurity 41 (CAS CATO-C4X-138541)
- Ponatinib Impurity 24【Discontinued,See C4X-22692】 (CAS CATO-C4X-226924)
- Cefadroxil Impurity 38 (CAS CATO-C4X-122438)
- tert-butyl 1H-pyrrolo[2,3-c]pyridine-1-carboxylate (CAS 370880-82-3)
- (S)-2-Amino-3-morpholinopropanoic acid (CAS 1931924-34-3)
- Methyl 3-amino-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate (CAS 1352400-99-7)
- 2-((4-Fluorobenzyl)oxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1346708-05-1)
- N-Methyl-1-(2,4,5,6-tetrahydrocyclopenta[c]-pyrazol-3-yl)methanamine dihydrochloride (CAS 893638-31-8)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com